Scientists have discovered a new antibiotic called Darobactin, produced by bacteria living inside soil-dwelling nematodes. This compound targets Gram-negative bacteria by binding to a previously unexploited protein on their outer…
Researchers at the Cleveland Clinic have discovered a previously unknown pathway through which excess niacin contributes to cardiovascular disease. The study identifies a metabolite called 4PY that triggers vascular inflammation,…
Scientists at the University of California, Irvine, have identified a signaling molecule called SCUBE3 that potently stimulates hair growth. The discovery stems from studying hairy skin moles and could lead…
Researchers at the National Institutes of Health and international partners have identified the hormone GDF15 as the primary cause of severe morning sickness. The study reveals that a woman's sensitivity…
Researchers at City of Hope have developed a small molecule called AOH1996 that targets a specific protein variant essential for cancer cell DNA replication. The drug has shown the ability…
A collaborative study between Roche and Harvard University has led to the discovery of Zosurabalpin, a new antibiotic class that effectively kills carbapenem-resistant Acinetobacter baumannii. The drug works by inhibiting…
Researchers have discovered that the protein Interleukin-11 (IL-11) acts as a major driver of aging and organ decline in mammals. By blocking this protein in animal models, scientists successfully extended…
Researchers at the University of Pennsylvania and Children's Hospital of Philadelphia have successfully used modified CAR-T cells to treat patients with severe lupus. The therapy effectively reboots the immune system…
Scientists in Costa Rica have discovered that the dense fur of two-fingered and three-fingered sloths hosts a diverse ecosystem of microbes that produce potent antibiotic compounds. These findings suggest that…
