An international team of researchers known as the Zoonomia Project has utilized artificial intelligence to analyze the genomes of 240 mammalian species. By identifying genetic sequences that have remained unchanged…
NIH scientists have discovered that age-related mutations in blood stem cells, a condition called CHIP, significantly increase the risk of heart disease by triggering chronic inflammation. The study explains how…
Researchers at the National Institutes of Health and international partners have identified the hormone GDF15 as the primary cause of severe morning sickness. The study reveals that a woman's sensitivity…
Scientists have identified extrachromosomal DNA (ecDNA) as a key factor in how tumors evolve and resist chemotherapy. These circular DNA fragments carry oncogenes and replicate independently, allowing cancer cells to…
Regeneron Pharmaceuticals has demonstrated that its gene therapy, DB-OTO, can restore hearing in children born with profound deafness due to OTOF gene mutations. The therapy uses a dual-vector viral system…
Researchers at Mass General Brigham have identified a rare genetic variant in the RELN gene that protected a man from Alzheimer's symptoms for nearly three decades. This discovery highlights a…
A global research team has identified "Obelisks," a new class of viroid-like genetic entities found in the human gut and mouth. These circular RNA structures are distinct from known viruses…
Researchers at the National Institutes of Health identified a genetic disorder called DADA2 that causes early-onset strokes and chronic inflammation. By pinpointing mutations in the ADA2 gene, the team developed…
Researchers at Mount Sinai have discovered that spaceflight can lead to somatic mutations in the blood-forming stem cells of astronauts. These mutations, known as clonal hematopoiesis, were found at higher-than-expected…
